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3088b857
3088b857
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2021-07-13
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3088b857
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2021-06-22
Oh
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3088b857
3088b857
·
2021-06-21
Nice
Orphazyme rose more than 6% in premarket trading
(June 21) Orphazyme rose more than 6% in premarket trading. What happened Shares of Orphazyme, a c
Orphazyme rose more than 6% in premarket trading
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3088b857
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2021-06-21
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3088b857
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2021-06-19
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3088b857
3088b857
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2021-06-18
[Doubt]
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3088b857
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2021-06-18
[Lovely]
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3088b857
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2021-06-18
Tell me your opinion about this news...
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3088b857
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2021-06-18
[Strong]
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3088b857
3088b857
·
2021-06-18
[Smile] [Smile]
Ford Lifts Profit Guidance While F-150 Lightning, New Vehicles See Strong Demand
Ford joined GM with upbeat earnings guidance and sees strong reservations for critical new vehicles including its first electric truck.
Ford Lifts Profit Guidance While F-150 Lightning, New Vehicles See Strong Demand
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Drug Administration (FDA) refused to approve an application for the company's lead candidate. 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Arimoclomol also failed to improve patients' scores on a secondary endpoint specifically requested by the FDA.</p>\n<p><b>Now what</b></p>\n<p>According to Orphazyme, the company needs to further substantiate the validity of the primary endpoint that arimoclomol almost achieved. To satisfy the FDA, the company will most likely have to run a new pivotal study.</p>\n<p>Some shareholders remain hopeful that the European Medicines Agency will be less strict than the FDA. While the FDA's European colleague has been more lenient regarding treatments for rare diseases in the past, arimoclomol probably isn't moving forward until it produces some convincing clinical-trial results.</p>\n<p>Despite lacking a clear path forward, the Denmark-headquartered company still boasts a fairly large market cap in excess of $500 million at recent prices. Irrational expectations could keep it elevated, but this is way too high for anyclinical-stage biotechin Orphazyme's position.</p>\n<p></p>\n<p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Orphazyme rose more than 6% in premarket trading </title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nOrphazyme rose more than 6% in premarket trading \n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time\">2021-06-21 17:17</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>(June 21) Orphazyme rose more than 6% in premarket trading. </p>\n<p><img src=\"https://static.tigerbbs.com/a1e2eb27cc68ce74ddd21a64a64634cf\" tg-width=\"719\" tg-height=\"495\" referrerpolicy=\"no-referrer\"></p>\n<p><b>What happened</b></p>\n<p>Shares of <b>Orphazyme</b>, a clinical-stage biopharmaceutical company, got hammered after the Food and Drug Administration (FDA) refused to approve an application for the company's lead candidate. Investors are now uncertain when the biotech could have an approved product to sell, and pushed the stock 44.4% lower as of 12:12 p.m. EDT on last Friday.</p>\n<p><b>So what</b></p>\n<p>The FDA began reviewing an application for Orphazyme's lead candidate arimoclomol last September as a potential treatment for a rare but life-threatening disease called Neimann-Pick Disease Type-C (NPC). Earlier this month, shares of Orphazymeshot upmore than 200% in anticipation of a green light that never came.</p>\n<p>Instead of an approval decision for arimoclomol, the agency asked for more information in the form of a complete response letter (CRL). That came as a shock to heaps of investors who were new to the complex world of drug development and were expecting a massiveshort squeeze.</p>\n<p>Many institutional investors were betting against Orphazyme because its lead candidate failed to achieve the primary endpoint in the pivotal study underpinning the application. Arimoclomol also failed to improve patients' scores on a secondary endpoint specifically requested by the FDA.</p>\n<p><b>Now what</b></p>\n<p>According to Orphazyme, the company needs to further substantiate the validity of the primary endpoint that arimoclomol almost achieved. To satisfy the FDA, the company will most likely have to run a new pivotal study.</p>\n<p>Some shareholders remain hopeful that the European Medicines Agency will be less strict than the FDA. While the FDA's European colleague has been more lenient regarding treatments for rare diseases in the past, arimoclomol probably isn't moving forward until it produces some convincing clinical-trial results.</p>\n<p>Despite lacking a clear path forward, the Denmark-headquartered company still boasts a fairly large market cap in excess of $500 million at recent prices. Irrational expectations could keep it elevated, but this is way too high for anyclinical-stage biotechin Orphazyme's position.</p>\n<p></p>\n<p></p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1184501396","content_text":"(June 21) Orphazyme rose more than 6% in premarket trading. \n\nWhat happened\nShares of Orphazyme, a clinical-stage biopharmaceutical company, got hammered after the Food and Drug Administration (FDA) refused to approve an application for the company's lead candidate. Investors are now uncertain when the biotech could have an approved product to sell, and pushed the stock 44.4% lower as of 12:12 p.m. EDT on last Friday.\nSo what\nThe FDA began reviewing an application for Orphazyme's lead candidate arimoclomol last September as a potential treatment for a rare but life-threatening disease called Neimann-Pick Disease Type-C (NPC). Earlier this month, shares of Orphazymeshot upmore than 200% in anticipation of a green light that never came.\nInstead of an approval decision for arimoclomol, the agency asked for more information in the form of a complete response letter (CRL). That came as a shock to heaps of investors who were new to the complex world of drug development and were expecting a massiveshort squeeze.\nMany institutional investors were betting against Orphazyme because its lead candidate failed to achieve the primary endpoint in the pivotal study underpinning the application. Arimoclomol also failed to improve patients' scores on a secondary endpoint specifically requested by the FDA.\nNow what\nAccording to Orphazyme, the company needs to further substantiate the validity of the primary endpoint that arimoclomol almost achieved. To satisfy the FDA, the company will most likely have to run a new pivotal study.\nSome shareholders remain hopeful that the European Medicines Agency will be less strict than the FDA. While the FDA's European colleague has been more lenient regarding treatments for rare diseases in the past, arimoclomol probably isn't moving forward until it produces some convincing clinical-trial results.\nDespite lacking a clear path forward, the Denmark-headquartered company still boasts a fairly large market cap in excess of $500 million at recent prices. Irrational expectations could keep it elevated, but this is way too high for anyclinical-stage biotechin Orphazyme's 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[Smile]","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/168528788","repostId":"2144742524","repostType":4,"repost":{"id":"2144742524","kind":"highlight","weMediaInfo":{"introduction":"The leading daily newsletter for the latest financial and business news. 33Yrs Helping Stock Investors with Investing Insights, Tools, News & More.","home_visible":0,"media_name":"Investors","id":"1085713068","head_image":"https://static.tigerbbs.com/608dd68a89ed486e18f64efe3136266c"},"pubTimestamp":1623942517,"share":"https://www.laohu8.com/m/news/2144742524?lang=&edition=full","pubTime":"2021-06-17 23:08","market":"us","language":"en","title":"Ford Lifts Profit Guidance While F-150 Lightning, New Vehicles See Strong Demand","url":"https://stock-news.laohu8.com/highlight/detail?id=2144742524","media":"Investors","summary":"Ford joined GM with upbeat earnings guidance and sees strong reservations for critical new vehicles including its first electric truck.","content":"<p><b>Ford</b> joined <b>General Motors</b> with upbeat earnings guidance and sees strong reservations for critical new vehicles including its first electric truck. Ford stock rose.</p>\n<p>The No. 2 U.S. auto giant said Thursday that it expects adjusted pretax earnings for the second quarter to surpass its own expectations and be \"significantly better\" than a year ago.</p>\n<p>That's despite the semiconductor shortage, which Ford said April 28 would halve its planned Q2 production and reduce full-year adjusted EBIT to $5.5 billion-$6.5 billion.</p>\n<p>Ford did not offer specific Q2 guidance on April 28 or Thursday. It will report for Q2 and offer outlook for the rest of the year July 28.</p>\n<p>On Wednesday, GM forecast adjusted earnings before taxes of $8.5 billion-$9.5 billion in the first half of 2021, up from an earlier view for $5.5 billion, due to strong demand for its SUVs and trucks. GM remains cautious for the full year.</p>\n<p>Also Thursday, Ford touted 100,000 reservations for the F-150 Lightning, its first all-electric pickup truck and <b>Tesla</b> Cybertruck rival. That's up from 20,000 reported May 20 after a launch event, and 70,000 on May 26.</p>\n<p>Meanwhile, its new compact Maverick truck has 36,000 reservations, just a week after unveiling. Ford also reported 20,000 reservations for the all-electric E-Transit commercial van and 190,000 for the new, full-size Bronco SUV.</p>\n<p>CEO Jim Farley will further address Q2 financial guidance at a Deutsche Bank auto industry conference Thursday afternoon.</p>\n<h2>Ford Stock</h2>\n<p>Shares rose 1.3% to 15.22 in Thursday's stock market. Ford stock, on the IBD Leaderboard, is extended from a cup-without-handle 13.72 buy point, cleared late May on its bold EV shift. GM stock eased 1% to 61.07 as it eyes a 63.54 cup-shaped buy point.</p>\n<p>On Wednesday, GM announced it will invest $35 billion to develop electric vehicles (EVs) and autonomous vehicles (AVs) through 2025. That's a 30% increase from its most recent forecast for $27 billion set last November, and a 75% increase from an initial forecast of $20 billion set in March 2020.</p>\n<p>By comparison, Ford in May announced $30 billion on EV- AV spending through 2025, up from a prior view for $22 billion.</p>\n<p>But Ford's investments include years prior to 2020, while GM's spending is for 2020 through 2025.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Ford Lifts Profit Guidance While F-150 Lightning, New Vehicles See Strong Demand</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nFord Lifts Profit Guidance While F-150 Lightning, New Vehicles See Strong Demand\n</h2>\n\n<h4 class=\"meta\">\n\n\n<div class=\"head\" \">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/608dd68a89ed486e18f64efe3136266c);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Investors </p>\n<p class=\"h-time\">2021-06-17 23:08</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<p><b>Ford</b> joined <b>General Motors</b> with upbeat earnings guidance and sees strong reservations for critical new vehicles including its first electric truck. Ford stock rose.</p>\n<p>The No. 2 U.S. auto giant said Thursday that it expects adjusted pretax earnings for the second quarter to surpass its own expectations and be \"significantly better\" than a year ago.</p>\n<p>That's despite the semiconductor shortage, which Ford said April 28 would halve its planned Q2 production and reduce full-year adjusted EBIT to $5.5 billion-$6.5 billion.</p>\n<p>Ford did not offer specific Q2 guidance on April 28 or Thursday. It will report for Q2 and offer outlook for the rest of the year July 28.</p>\n<p>On Wednesday, GM forecast adjusted earnings before taxes of $8.5 billion-$9.5 billion in the first half of 2021, up from an earlier view for $5.5 billion, due to strong demand for its SUVs and trucks. GM remains cautious for the full year.</p>\n<p>Also Thursday, Ford touted 100,000 reservations for the F-150 Lightning, its first all-electric pickup truck and <b>Tesla</b> Cybertruck rival. That's up from 20,000 reported May 20 after a launch event, and 70,000 on May 26.</p>\n<p>Meanwhile, its new compact Maverick truck has 36,000 reservations, just a week after unveiling. Ford also reported 20,000 reservations for the all-electric E-Transit commercial van and 190,000 for the new, full-size Bronco SUV.</p>\n<p>CEO Jim Farley will further address Q2 financial guidance at a Deutsche Bank auto industry conference Thursday afternoon.</p>\n<h2>Ford Stock</h2>\n<p>Shares rose 1.3% to 15.22 in Thursday's stock market. Ford stock, on the IBD Leaderboard, is extended from a cup-without-handle 13.72 buy point, cleared late May on its bold EV shift. GM stock eased 1% to 61.07 as it eyes a 63.54 cup-shaped buy point.</p>\n<p>On Wednesday, GM announced it will invest $35 billion to develop electric vehicles (EVs) and autonomous vehicles (AVs) through 2025. That's a 30% increase from its most recent forecast for $27 billion set last November, and a 75% increase from an initial forecast of $20 billion set in March 2020.</p>\n<p>By comparison, Ford in May announced $30 billion on EV- AV spending through 2025, up from a prior view for $22 billion.</p>\n<p>But Ford's investments include years prior to 2020, while GM's spending is for 2020 through 2025.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"F":"福特汽车","NGD":"New Gold"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2144742524","content_text":"Ford joined General Motors with upbeat earnings guidance and sees strong reservations for critical new vehicles including its first electric truck. Ford stock rose.\nThe No. 2 U.S. auto giant said Thursday that it expects adjusted pretax earnings for the second quarter to surpass its own expectations and be \"significantly better\" than a year ago.\nThat's despite the semiconductor shortage, which Ford said April 28 would halve its planned Q2 production and reduce full-year adjusted EBIT to $5.5 billion-$6.5 billion.\nFord did not offer specific Q2 guidance on April 28 or Thursday. It will report for Q2 and offer outlook for the rest of the year July 28.\nOn Wednesday, GM forecast adjusted earnings before taxes of $8.5 billion-$9.5 billion in the first half of 2021, up from an earlier view for $5.5 billion, due to strong demand for its SUVs and trucks. GM remains cautious for the full year.\nAlso Thursday, Ford touted 100,000 reservations for the F-150 Lightning, its first all-electric pickup truck and Tesla Cybertruck rival. That's up from 20,000 reported May 20 after a launch event, and 70,000 on May 26.\nMeanwhile, its new compact Maverick truck has 36,000 reservations, just a week after unveiling. Ford also reported 20,000 reservations for the all-electric E-Transit commercial van and 190,000 for the new, full-size Bronco SUV.\nCEO Jim Farley will further address Q2 financial guidance at a Deutsche Bank auto industry conference Thursday afternoon.\nFord Stock\nShares rose 1.3% to 15.22 in Thursday's stock market. Ford stock, on the IBD Leaderboard, is extended from a cup-without-handle 13.72 buy point, cleared late May on its bold EV shift. GM stock eased 1% to 61.07 as it eyes a 63.54 cup-shaped buy point.\nOn Wednesday, GM announced it will invest $35 billion to develop electric vehicles (EVs) and autonomous vehicles (AVs) through 2025. That's a 30% increase from its most recent forecast for $27 billion set last November, and a 75% increase from an initial forecast of $20 billion set in March 2020.\nBy comparison, Ford in May announced $30 billion on EV- AV spending through 2025, up from a prior view for $22 billion.\nBut Ford's investments include years prior to 2020, while GM's spending is for 2020 through 2025.","news_type":1},"isVote":1,"tweetType":1,"viewCount":441,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"defaultTab":"followers","isTTM":false}